Juxtaglomerular Cell Tumor
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
Juxtaglomerular cell tumor is highly vascular and consists of small venules, muscular arterioles, and capillaries interposed between monomorphic tumor cells. Branching vessels with "stag-horn" configuration resembling those seen in hemangiopericytoma may also be present. This image shows large sinusoidal vascular spaces separating cords of tumor cells. The tumor arises from juxtaglomerular cells - a component of the juxtaglomerular apparatus which plays a role in regulating blood pressure via renin release.