Granular Cell Tumor in Scrotum
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
Strong immunoreactivity for S-100 was seen in this case. Most granular cell tumors pursue a benign course. There are well-documented cases of "benign-appearing" granular cell tumors that produced distant metastases. Features favoring malignancy include necrosis, high mitotic activity, spindling of tumor cells, and prominent nucleoli.