funds for acquiring users and we do not seek funds for our existing collection or for technology development.

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There is a 5-50% diagnostic discordance between oncologic pathologists across all cancer types and practice settings, impacting grading and treatment planning. There are additional specific diagnostic issues for several cancers that have specific individual impacts on the outcomes from precision medicine and therapy. Diagnostic concordance has been identified as a critical issue in poor patient outcomes by the Institute of Medicine (IOM). Educational need Oncologic pathologists and oncologists need greater access to academically validated educational resources that will allow them to more accurately diagnose and grade tumors at the point of diagnosis, thereby supporting optimal treatment planning. Learning objective Increase diagnostic concordance by providing comprehensive expert- and community- validated morphologic images and relevant emerging research at the time of diagnosis and treatment planning. Educational methods WebPathology has one of the largest online collections of anatomic pathology images (13,000+ curated images, 90% of which represent tumors), serving about 54,000 unique visitors each month (average of 12 page views per user and 1.4 million events/ month). By converting this educational resource into a concordance platform, oncologic physicians can now review a case against expert and community validated images along with molecular correlates and emerging research data as available. This addresses, for the first time, all of the four ways the College of American Pathologists (CAP) has recommended addressing the issue of diagnostic discordance. Given the clear demand already demonstrated by our site usage, we propose to add educational value by: • Appointing an expert faculty panel to curate images for each subspecialty and organ system. • Adding up to 73,000 high-quality images from our archive across pathology subspecialties curated and contextualized by expert faculty. • Integrating a proprietary technology for related and relevant emerging literature. • Expert-led tumor board case of the month and weekly updates for each subspecialty and major disease are that are pushed on integrated social media. • Integrating social features that allow visitors to submit and comment on images, thereby supporting community discussion on an accurate diagnosis as recommended by CAP and IOM. Intended HCP audience Oncologic pathologists, surgical oncologists, medical oncologists and radiation oncologists, globally. HCP communications WebPathology already serves an exceptionally large and unique audience through organic traffic and direct visitors. We do not seek funds for acquiring users and we do not seek funds for our existing collection or for technology development. We will register our users organically by offering educational value as described above.

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