Alcoholic Cirrhosis : Regenerative Nodule

Alcoholic liver disease comprises a spectrum of pathologic changes, including uncomplicated steatosis, steatohepatitis, and cirrhosis. Cirrhosis, the final irreversible pathologic change, occurs in about 10% of chronic alcoholics. Diffuse parenchymal micronodularity (< 3mm), as seen here, is due to underlying fibrosis. Larger regenerative nodules are associated with periodic abstinence, which allows regeneration of hepatocytes. Image Copyright: pathorama.ch.