Alcoholic Steatohepatitis
Image Description
The main pathologic features of alcoholic steatohepatitis include macrovesicular steatosis, hepatocellular damage, inflammation, and pericellular fibrosis. The hepatocellular damage manifests with hepatocyte ballooning, cytoplasmic clearing, and intracytoplasmic Mallory-Denk bodies (Mallory's hyaline). A few hepatocytes show microvesicular steatotis as well in this image. Due to altered intestinal iron absorption in chronic alcohol abuse, Kupffer cells and hepatocytes may also show mild, non-zonal iron overload.