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Image Description

In juvenile polyposis syndrome, there is increased risk of developing adenocarcinoma due to dysplastic epithelium with a juvenile polyp or in a coexistant adenoma. About 30% to 50% of individuals develop adenocarcinoma by age 45.

This image shows a juvenile polyp from a patient with juvenile polyposis syndrome. The lining epithelium is dysplastic and resembles that seen in tubular adenomas. Note the distorted and cystically dilated glands and the expanded edematous lamina propria.

Image 23 of 45