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Mucinous Carcinoma of Gallbladder: Intracytoplasmic and/or intraluminal mucin is often seen in gallbladder carcinomas. In contrast, stromal mucin pools are found in < 10% of cases. When > 50% of the tumor is composed of well-defined mucin pools with detached clusters of carcinoma cells, it qualifies as mucinous carcinoma.

Pure mucinous (colloid) carcinomas of gallbladder are exceedingly rare. Most cases contain conventional adenocarcinomatous areas. They are large, bulky tumors that present at an advanced stage and have a poor prognosis. The clinical presentation can mimic acute cholecystitis.

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