PAS stain showing yeast-forms as well as fungal hyphae in a background of squamous debris from a case of candida esophagitis.
Image courtesy of: @PatholWalker
About the Disease
Esophageal infections can be caused by fungi, bacteria, viruses, and parasites. The most common agents are Candida, Herpes Simplex Virus, and Cytomegalovirus. In South America, Trypanosoma cruzi is an important cause of esophagitis leading to megaesophagus.