Melanoma Immunohistochemistry : CAM5.2

Metastatic melanoma in liver (FNA specimen, Clot Section, CAM5.2 immunostain). Native liver tissue is strongly positive, while the tumor cells are weakly positive. CAM5.2 can be positive in up to 10% of melanomas. Cytokeratins AE1/AE3 was negative in this case. Image courtesy of : Ed Uthman, Houston, Texas, USA.