Fibrocystic Change : Apocrine metaplasia
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Apocrine metaplasia is a frequent finding in fibrocystic change. The lining cells have abundant eosinophilic granular cytoplasm, prominent nucleolus and apocrine snouts. Immunostain for GCDFP-15 is strongly positive. Presence of cytologic atypia in apocrine metaplasia is not a risk factor for carcinoma.