DLBCL : Spleen
Diffuse large B-cell lymphoma (DLBCL) of the spleen often produces solitary or multiple, well-demarcated large nodules that may result in splenomegaly. Foci of necrosis may be present. The splenic involvement may be primary or secondary. The image shows DLBCL of spleen in a 47 y/o male. Image copyright: Pathorama.ch.