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Granulomatous Cystitis : Post-BCG

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The treatment of high-grade papillary urothelial carcinoma and urothelial carcinoma-in-situ by intravesical BCG therapy is followed by intense granulomatous inflammation. The image shows small and large non-caseating granulomas in the lamina propria composed of epithelioid histiocytes and multinucleated giant cells. The granulomas are surrounded by lymphocytic infiltrate.

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