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DLBCL : Lymph Node

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Patients with diffuse large B-cell lymphoma (DLBCL) present with rapidly enlarging lymph nodes or tumor masses (in case of extranodal involvement seen in about 40% of cases). This cervical lymphadenectomy specimen from a 45 y/o male shows several enlarged lymph nodes with a fleshy pink-tan cut surface. The nodal architecture is completely effaced. The diagnosis of DLBCL was confirmed with the help of immunostains (positive for CD20, CD22, IgM kappa).

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