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Adamantinomatous Craniopharyngioma

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Craniopharyngioma is an epithelial neoplasm with solid and cystic components as depicted in this image. The eosinophilic areas on top left represent nodules of plump anucleate squamous cells - the so called "wet keratin." Craniopharyngiomas are subdivided into two types based on morphologic features: 1) Adamantinomatous (90% of cases) seen most in children and 2) Papillary (10% of cases) seen mostly in adults. The image shows adamantinomatous type.

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