Facebook Icon Twitter icon Instagram icon Feedback

Insulinoma : Molecular Genetics

prev slide 7 of 9 next
No Image
Pancreas_PanNET58_Insulinoma.jpg

Close

Comments:
Molecular Pathogenesis of Insulinomas: Sporadic solitary insulinomas are of unknown origin. Patients with germline mutations in MEN1 gene develop insulinomas among other PanNET. Insulinomas arising in the setting of familial insulinomatosis are associated with germline mutations in MAFA gene. Additional comments on the molecular pathogenesis of insulinomas are under non-functioning pancreatic neuroendocrine tumors.

The image shows insulinoma composed of anastomosing trabeculae on the right and normal pancreas on the upper left.

prev slide 7 of 9 next