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Embryonal Carcinoma : CD30

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Comments:
Immunohistochemical Profile of Ovarian Embryonal Carcinoma: It is similar to their testicular counterpart, with minor differences. STRONGLY POSITIVE MARKERS: cytokeratin, CD30, PLAP, SALL4, and OCT4; SOMETIMES POSITIVE: SOX2 (50% of cases), AFP (focal expression in one-third of cases), beta-hCG (limited to syncytiotrophoblast), and NSE; NEGATIVE MARKERS: CD117, EMA, CEA, glypican-3, and vimentin.

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