High-grade Serous Carcinoma
High-grade papillary serous carcinoma of ovary. The tumor infiltrates the serosal surface. The specimen includes uterus and right adnexa from a 69 y/o female. Image copyright: pathorama.ch. The ovarian tumors with predominantly surface growth and minimal/absent parenchymal invasion and intracystic growth are labeled Serous Surface Papillary Carcinomas. When the bulk of the tumor consists of extraovarian serous carcinoma with only focal (<0.5 cm) surface growth on the ovaries, it is considered primary peritoneal serous carcinoma with involvement of the ovaries.