Gout : Histology

Comments:
Monosodium urate crystals are highly water soluble and easily get removed from tissue sections during aqueous processing, leaving behind homogenous, amorphous pink or amphophilic deposits without residual crystals. If the tissue concentration of urate is very high, some crystals may survive usual paraffin processing (seen in the center of this image as brownish clusters).

Image courtesy of: Dr. Ibrahim Zardawi; used with permission.