Juvenile Polyp : Malignant Potential
Sporadic juvenile polyps have no malignant potential. Once resected, they do not recur. In juvenile polyposis syndrome, there is increased risk of developing adenocarcinoma due to dysplastic epithelium with a juvenile polyp or in a coexistant adenoma. About 30% to 50% of individuals develop adenocarcinoma by age 45. In juvenile polyps, surface ulceration is common. The regenerating epithelium (shown here) adjacent to ulcer and granulation tissue may be mistaken for dysplasia.