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AdenoCA of Colon : Histologic Grading

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Colon_AdenoCA107.jpg

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Colo-rectal adenocarcinomas with <50% gland formation are high-grade (poorly-differentiated) and have adverse prognosis. Tumors with at least 50% gland formation are low-grade (well- and moderately-differentiated). This image is a higher magnification of the previous case showing a well-differentiated adenocarcinoma of sigmoid colon.

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