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Crohn Disease : Microscopic

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During the active phase of Crohn disease, numerous neutrophils infiltrate within crypt epithelium (cryptitis) or accumulate in the crypt lumen (crypt abscess) (shown here). There is associated crypt destruction with ulceration.

Ulcerated and non-ulcerated histologically-normal areas are sharply demarcated from each other. Image courtesy of Dr. Jean-Christophe Fournet, Paris, France; humpath.com; Used with permission.

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