Sclerosing mediastinitis
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Another case of sclerosing mediastinitis. The patient was a young female who presented with a mass in middle mediastinum. Histologic findings included dense fibrosis, chronic lympho-plasmacytic infiltrate, and widespread calcification. Many cases of chronic mediastinitis are caused by Histoplasma or Mycobacteria. In many cases, no cause can be ascertained (idiopathic sclerosing mediastinitis).