Sebaceous Carcinoma : PMS2 expression

This image shows intact expression of PMS2 (one of the genes involved in DNA mismatch repair function) in sebaceous carcinoma from a patient with Muir-Torre syndrome. The tumor was positive for MLH1 but negative for MSH2 and MSH6 (see previous three images). Image courtesy of: Marcelo Balancin, MD, Sao Paulo, Brazil.