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Peripheral Ossifying Fibroma : Differential Diagnosis

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Differential Diagnosis of peripheral ossifying fibroma (POF) includes irritation fibroma, pyogenic granuloma, and peripheral giant cell granuloma. This image of a POF shows a bland spindle cell proliferation under squamous mucosa that is intact on the left and ulcerated on the right. The deeper aspects of the lesion show osteoid matrix. Image courtesy of: Dr. Ibrahim Zardawi; used with permission.

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