Striving to be the most comprehensive online resource for high-quality pathology images

 

Wilson Disease

prev  
slide 13 of 32
next
No Image
Liver_WilsonDz4.jpg

Close

Comments:
Wilson disease is an uncommon autosomal recessive disorder due to mutations in the ATP7B gene, which disrupt normal hepatic copper transport, leading to copper accumulation in hepatocytes and progression from steatosis to chronic hepatitis to cirrhosis. Hepatocytes within the cirrhotic nodules show steatosis, ballooning degeneration, focally dense eosinophilic cytoplasm, cholestasis, large irregular lipofuscin granules, and occasional Mallory bodies (upper left).

prev
slide 13 of 32
next