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Canalicular Adenoma

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Canalicular adenoma is a benign neoplasm of a salivary glands which originally was considered to be a variant of basal cell adenoma. It is most common in the 7th decade of life but can occur from 4th to 9th decades of life. It has a greater tendency to involve the minor salivary glands. Approximately 70%-90% of the tumors occur in the oral cavity and is particularly common in the upper lip. Infrequently palate, buccal mucosa and parotid gland may be involved. Patients usually present with painless, slowly enlarging nodule.

This low power image of a canalicular adenoma shows a well-circumscribed nodule composed of basaloid bi-layered epithelium arranged in cords, rows and interconnecting tubules reminiscent of canals (right side). There is rim of normal submucous salivary gland parenchyma and overlying normal oral mucosa (left side).

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