Striving to be the most comprehensive online resource for high-quality pathology images

 

Adenocarcinoma of Lung : Definition

 
slide 1 of 128
next
No Image
Lung_AdenoCA_Gross1.jpg

Close

Comments:
Adenocarcinomas of the lung are malignant epithelial tumors that show glandular differentiation, mucin production, or expression of pneumocyte markers (TTF1, Napsin-A).

Most invasive adenocarcinomas are usually gray-white nodules with spicules of black anthracotic pigment. The usual location is peripheral and the overlying pleura may be puckered. The tumor boundaries may be ill-defined grossly due to the lepidic component which spreads into the surrounding lung parenchyma.

In rare cases, cells from a peripherally located adenocarcinoma may gain access to the pleural cavity and spread diffusely along the pleural surfaces grossly simulating a malignant mesothelioma (pseudomesotheliomatous carcinoma). Image copyright: pathorama.ch

slide 1 of 128
next