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Papillary Cystadenoma

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Papillary cystadenoma is a benign tumor that accounts for about 35% of all primary epididymal neoplasms. About 40% are bilateral and these cases are usually seen in the setting of von Hippel-Lindau syndrome. Molecular studies have shown allelic deletion of VHL gene in papillary cystadenoma of epididymis and related lesions. The tumor consists of dilated ducts containing papillary structures lined by cuboidal or columnar epithelium. The cells have clear to lightly eosinphilic cytoplasm. Shen T, et al. Int J Surg Pathol 2000 Jul; 8(3):207-212. Image copyright: pathorama.ch

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