Follow us:        
11,389 Images : Last Website Update : Nov 11, 2021

Follicular Dendritic Cell Sarcoma : Clinical Features

prev
slide 3 of 36
next
No Image
HemePath_FollDendCellSarcoma4.jpg

Close

Comments:
Clinical Presentation of Follicular Dendritic Cell Sarcoma (FDCS): About 70% of cases involve lymph nodes. The most common presentation is painless, slowly enlarging lymph nodes (usually cervical). Other lymph node groups (axillary, mediastinal, mesenteric, retroperitoneal, and supraclavicular) are also frequently involved.

Extranodal sites make up the remainder 30% of cases. They include oral cavity (tonsils, palate), pharynx, neck, thyroid, axilla, gastrointestinal tract (stomach, colon), spleen, liver, mediastinum, lung, mesentery, retroperitoneal soft tissues, and breast. Systemic symptoms are uncommon.

This image shows FDCS arising in colon. There is proliferation of a uniform population of spindle cells in fascicular, storiform, and whorled patterns. The spindle cells are admixed with an inflammatory infiltrate of small lymphocytes and plasma cells.

prev
slide 3 of 36
next