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LCH : Nuclear Features

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The nuclei of Langerhans cells lack cytologic atypia and have a distinctive complex, folded, indented, or grooved appearance. Several nuclei are seen in this transmission electron micrograph. The nuclear chromatin is finely dispersed and nucleoli are not prominent.

Image courtesy of: John Brealey (@JohnBrealey), Senior Medical Scientist, Electron Microscopy Unit, SA Pathology, Australia; used with permission.

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