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Lymphomatoid Granulomatosis

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This image shows angiocentric and angioinvasive growth pattern of the lymphoid infiltrates in lymphomatoid granulomatosis (LG).

The infiltrate is polymorphous and consists of small lymphocytes (mostly reactive T-cells), histiocytes, immunoblasts, and EBV-positive large atypical lymphoid cells. The number of EBV-positive cells varies within and among nodules and forms the basis of grading of LG.

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