Striving to be the most comprehensive online resource for high-quality pathology images

 

Neuroblastoma Maturation : Post-Chemotherapy

prev  
slide 60 of 60
No Image
Adrenal_GNB12.jpg

Close

Comments:
The histologic changes in neuroblastomas induced by chemotherapy/radiation therapy include extensive necrosis, hemorrhage, hemosiderin deposition (shown here), fibrosis, and calcification along with varying degrees of tumor maturation. This image shows maturation to ganglioneuroblastoma following chemotherapy. The differentiating neuroblasts have moderate to abundant acidophilic or amphophilic cytoplasm and an enlarged eccentric vesicular nucleus with a single prominent nucleolus. There is abundant neuropil in the background.

prev
slide 60 of 60