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Clear Cell Sarcoma of Kidney

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In its classic form, the clear cell sarcoma of kidney (CCSK) consists of nests, cords, and sheets of somewhat monomorphic tumor cells with scant cytoplasm and a high nucleus:cytoplasmic ratio. The tumor has a prominent network of delicate vasculature (chicken wire pattern similar to that seen in myxoid liposarcoma). The term "Clear Cell" is a misnomer since the clear cell appearance is caused not by the cytoplasm but is the result of loose spacing of tumor cells with intervening clear mucoid matrix.

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