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Gemistocytic Astrocytoma, WHO Grade II

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Comments:
Note the dense eosinophilic cytoplasm and eccentrically displaced nucleus. Gemistocytes are frequently found in other fibrillary astrocytomas and oligodendrogliomas. Some authors require at 20% of tumor cells to be gemistocytic before using the designation of gemistocytic astrocytoma. This tumor appears to be composed of an almost pure population of gemistocytic cells.

slide 4 of 7