Comments:
The image shows the usual histologic features of leiomyosarcoma – interlacing fascicles of spindle cells with markedly atypical nuclei and increased mitotic activity. Distinction of leiomyosarcomas from leiomyomas arising in urinary bladder is based upon the presence of infiltrative borders, mitotic activity, coagulative necrosis, and cellular atypia in the former. Am J Surg Pathol; 2002 Mar; 26(3):292-300.
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