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Adenocarcinoma-in-situ of Cervix

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Comments:
High power view showing neoplastic cells lining the glandular papillae. Numerous apoptotic bodies are also seen. More than half of adenocarcinoma-in-situ cases of cervix show associated squamous CIN. Treatment is usually by cone biopsy. Many cases recur despite negative margins, so close follow-up is necessary.

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