Comments:
High-grade papillary urothelial carcinomas display total architectural disorganization and significant cytologic atypia of urothelium that can be recognized even at low power. There is loss of nuclear polarity; considerable variation in nuclear size, shape, and chromatin content; mitoses are frequent and may be abnormal. Umbrella cells are usually absent.
return to Papillary Urothelial Carcinoma
