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Fibroma of Tendon Sheath : Immunostains

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SoftTissue_FibromaOfTendonSheath5.jpg

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Fibroma of tendon sheath is usually positive for muscle-specific actin and smooth muscle actin but not desmin. Markers of histiocytic differentiation (CD68, HAM56) may be positive in some cases.

The image shows a focus of myxoid change with bland stellate and spindle cells in loose myxoid stroma.

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