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Silicone Lymphadenopathy

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Silicone may escape from implants due to rupture, leak, or simply by “bleeding” through the surface of an intact implant and carried to the regional draining lymph nodes causing adenopathy. The image shows presence of silicone as a refractile, non-staining, and non-polarizable material within histiocytes creating a foamy or bubbly appearance. Silicone can be identified by infrared microspectroscopy or radiographic microanalysis in tissue samples.

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