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Agnogenic Myeloid Metaplasia

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Comments:
A clonal chronic myeloproliferative disorder with anemia, progressive bone marrow fibrosis, hepatosplenomegaly, and extra-medullary hematopoiesis. This splenectomy specimen shows evidence of extra-medullary hematopoiesis consisting of clusters of megakaryocytes and myeloid precursors.

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