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Angiosarcoma of Breast - Intermediate Grade

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Comments:
In intermediate grade angiosarcomas of the breast, the proliferating endothelial cells form small buds or papillary fronds projecting into the vascular lumens. The anastomosing vascular channels have narrow collapsed lumens imparting a more solid appearance. This tumor arose in a pregnant female. Note the lactational change in the lobule on the left.

slide 7 of 10