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Hepatoblastoma - Embryonal pattern

slide 11 of 64

Comments:
Epithelial hepatoblastoma may contain mixed embryonal (seen on the left) and fetal patterns (seen on the right). Embryonal areas appear less differentiated (immature), with disordered architecture, higher nuclear:cytoplasmic ratios, increased cellular atypia, and poorly-defined cell borders. Fetal areas comprise cords of relatively uniform tumor cells (mature) with abundant cytoplasm and minimal atypia, resembling mature hepatocytes.

slide 11 of 64