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Focal Nodular Hyperplasia : Gross

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Gross Pathology: Focal nodular hyperplasia (FNH) appears as a subcapsular, solitary, well-circumscribed (but unencapsulated), firm, coarsely nodular lesion with a central stellate scar. It may resemble macronodular cirrhosis. The size ranges from a < 1 cm to > 10 cm. It is yellow-gray or light brown and appears paler than adjacent liver parenchyma.

Fibrous strands radiate outwards from the depressed central scar and divide the lesion into nodules. Central scar may be poorly developed or absent in some cases. Some lesions are partially exophytic or even entirely pedunculated. Hemorrhage and necrosis are seen less frequently than in hepatocellular adenoma. The background liver is usually normal-appearing. Image copyright: pathorama.ch

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