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Cirrhosis in Liver Biopsy

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Comments:
On core needle biopsies, hepatic cirrhosis manifests with diffuse nodularity separating the parenchyma into regenerative nodules. The fibrous septa contain chronic inflammatory cell infiltrates and a ductular reaction. The distorted parenchymal architecture also shows abnormal vasculature due to hepatocyte damage and scarring.

slide 7 of 16