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Adenocarcinoma in Chronic Atrophic Gastritis

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Comments:
Intestinal-type gastric adenocarcinoma (top) in a background of chronic atrophic gastritis with intestinal metaplasia (bottom). Intestinal metaplasia is a precursor lesion to intestinal-type gastric carcinoma, and since metaplasia is often seen in autoimmune gastritis, these patients are at increased risk for malignancy (adenocarcinoma in addition to neuroendocrine tumors).

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