Striving to be the most comprehensive online resource for high-quality pathology images

 

Neural Fibrolipoma : Clinical Features

prev  
slide 2 of 9
next
No Image
NeuralFibrolipoma_resized.JPG

Close

Comments:
Sites: Neural fibrolipoma occurs more frequently in the upper extremities (74% of cases) than in the lower extremities (17%). The most commonly involved nerves are median nerve and its digital branches (>60% of cases), plantar nerve (11%), and radial or ulnar nerves (7%). Infrequently, it is bilateral, involves multiple nerves, or is limited to brachial plexus or cranial nerves.

Clinical Features: With median nerve involvement, it presents as a soft, slow growing mass on the volar aspects of the hands, wrists, and forearm in young individuals (within the first three decades of life). Many cases are present at birth or manifest during infancy. Only 10% of cases occur in individuals > 40 years of age.

The patients develop compression neuropathy due to the entrapment of the enlarged median nerve in the carpal tunnel. There is sensory loss, paresthesias, pain, tenderness, and muscle weakness. About one-third of patients have bone overgrowth and macrodactyly of the digits supplied by the affected nerve (as shown here). Macrodactyly is more common in females.

Case courtesy of Andrew Lawson, Radiopaedia.org. From the case rID: 28312

prev
slide 2 of 9
next