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Extranodal Rosai-Dorfman Disease : Skin

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The skin lesions of cutaneous Rosai-Dorfman disease are variable in size and consist of erythematous or red-brown papules, nodules or plaques usually involving the trunk and limbs. The lesions may occur singly, arise in clusters, or be widespread. The disease pursues a protracted but benign clinical course with partial or complete remission.

The image shows dense infiltrate of lymphocytes and histiocytes in the dermis and subcutis in a case of CRDD.

Image courtesy of: Vishwas Parekh, MD; used with permission.

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