Comments: This prostate needle biopsy was done in a middle-aged man for progressively rising PSA. It shows a spindle cell proliferation with abundant collagenous stroma containing a few inflammatory cells.
Comments: Rare mitotic figures were seen. The remainder of the biopsies showed moderate to severe chronic inflammation.The cells in question were negative for PSA and PAP and positive for vimentin. A diagnosis of inflammatory pseudotumor was rendered. The PSA came down with antibiotic therapy.