Genitourinary Tract

Genitourinary Tract

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Monday, September 06, 2010               
 
 Atypical Small Acinar Proliferations in Prostate
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1: Atypical Small Acinar Proliferation in Prostate
Comments: A serum PSA of 4.5 ng/ml resulted in this needle biopsy. Digital rectal examination and prostate ultrasound were normal. A single atypical focus (shown here) was found among 10 cores. The features are highly suspicious for adenocarcinoma, but were felt to be insufficient for an unequivocal diagnosis.
2: Atypical Small Acinar Proliferation in Prostate
Comments: Another example of atypical small acinar proliferation suspicious for but not diagnostic of malignancy. This case was reviewed by an expert who concurred with the atypical diagnosis. For some observers, this focus may be diagnostic of adenocarcinoma.
3: Atypical Glands in 1st Prostate Biopsy
Comments: Three atypical glands demonstrating rare prominent nucleoli. This was the only focus of concern among 12 cores.
4: Adenocarcinoma in Repeat Biopsy
Comments: A repeat biopsy performed three months later (same case as previous image) showed an unequivocal focus of adenocarcinoma (Gleason 3+3=6). Interestingly, the cancer was in a location different from the atypical focus in the previous biopsy
Last Updated: Tuesday, August 03, 2010
 
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